NHS Urges Caution: Avoid Dangerous Paracetamol Combinations

URGENT UPDATE: The NHS has issued a critical warning regarding the use of paracetamol, a common painkiller, advising against its combination with certain medications due to potential dangerous reactions. This alert affects countless individuals across the UK who rely on this widely available over-the-counter drug for managing pain from headaches, back pain, and colds.

As of October 2023, the NHS has released guidelines emphasizing that paracetamol is not safe for everyone, particularly for those taking warfarin, a medication that prevents blood clots. The health body states, “Paracetamol can increase the risk of bleeding if you take it [warfarin] regularly.” Individuals on warfarin should consult their GP before using paracetamol to avoid serious health risks.

The NHS clarifies, however, that combining low doses of paracetamol with warfarin can be safe. “It’s safe to take paracetamol while you’re on warfarin. But take the lowest dose that controls your pain,” they advised. Exceeding four 500mg tablets within 24 hours for more than a few days can lead to slower blood clotting, increasing the risk of bleeding.

Additionally, mixing paracetamol with other medications that also contain it, such as co-codamol or specific cold and flu treatments, poses a significant overdose risk. Fortunately, medications such as ibuprofen, aspirin, and codeine do not contain paracetamol and can be safely used in conjunction with it.

The NHS urges caution for those undergoing treatment for epilepsy or tuberculosis (TB). “Speak with your GP before taking paracetamol if you are on treatment for these conditions,” the health body advises, highlighting potential hazards in these combinations.

While paracetamol is generally safe when taken as directed, the NHS warns of potential interactions with herbal remedies and supplements. They state, “There’s not enough information to say whether complementary medicines are safe to take with paracetamol,” reinforcing the need for open communication with healthcare providers.

In rare cases, paracetamol may trigger severe allergic reactions. The NHS instructs individuals to call 999 immediately if they experience symptoms such as swelling of the lips, mouth, or throat, difficulty breathing, or skin discoloration.

For those relying on paracetamol for pain relief, this guidance is crucial. The NHS stresses the importance of understanding how to use this common medication safely. For further details, visit the NHS website.

This urgent advisory serves as a vital reminder for the public to remain vigilant about medication interactions and to prioritize safety when managing health conditions.